Manchester United troubles this season moved from bad to worse as their star goalkeeper is likely to miss their Premier League game with table toppers and unbeaten Liverpool.
The 28 year old goalkeeper limped off during Spain’s encounter with Sweden on Sunday.
He was then replaced by Chelsea shot stopper, Kepa Arrizabalaga with La Rojas held to a 1-1 draw in their Euro 2020 qualifier.
He adds to the long list of absentees for the Red Devils putting manager Ole Gunnar Solksjaer under a lot of pressure.
United are 12th in the Premier League and have not won in their past three top-flight games.
They will face a Liverpool side aiming for an 18th consecutive Premier League win, a total that would equal the record held by Manchester City.